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Simplovir

  • Simplovir – 400 mg

    Indications: For the treatment of viral infections due to herpes simplex virus (type I & II) and varicella zoster virus (herpes zoster & chickenpox). For the treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes. For the prophylaxis of herpes simplex infections in immunocompromised patients.

    Pharmacology: Acyclovir exerts its antiviral effect on herpes simplex viruses (HSV) and varicella-zoster virus by interfering with DNA synthesis and inhibiting viral replication. The exact mechanisms of action against other susceptible viruses have not fully elucidated. In vitro studies with herpes simplex viruses indicate that acyclovir triphosphate is the pharmacologically active form of the drug; the triphosphate functions as both a substrate for and preferential inhibitor of viral DNA polymerase.

    Therapeutic Class: Antivirals (Systemic Antifungal, Antiviral and Antiprotozoal Agents)
    Generic Name: Acyclovir
    Manufacturer: Incepta Pharmaceuticals Ltd.
  • Simplovir – 200 mg

    Indications: For the treatment of viral infections due to herpes simplex virus (type I & II) and varicella zoster virus (herpes zoster & chickenpox). For the treatment of herpes simplex virus infections of the skin and mucous membranes including initial and recurrent genital herpes. For the prophylaxis of herpes simplex infections in immunocompromised patients.

    Pharmacology: Acyclovir exerts its antiviral effect on herpes simplex viruses (HSV) and varicella-zoster virus by interfering with DNA synthesis and inhibiting viral replication. The exact mechanisms of action against other susceptible viruses have not fully elucidated. In vitro studies with herpes simplex viruses indicate that acyclovir triphosphate is the pharmacologically active form of the drug; the triphosphate functions as both a substrate for and preferential inhibitor of viral DNA polymerase.

    Therapeutic Class: Antivirals (Systemic Antifungal, Antiviral and Antiprotozoal Agents)
    Generic Name: Acyclovir
    Manufacturer: Incepta Pharmaceuticals Ltd.

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