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Anquil – IM/IV Injection 15 mg/3 ml-3 ml ampoule/pcs
৳ 75.00
Generic Name: Midazolam
Therapeutic class: Sedative-Hypnotic (CNS Preparations)
Manufacturer: General Pharmaceuticals Ltd
Note: চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications
Midazolam is indicated in-
- Short-term treatment of insomnia.
- Sedation in premedication before surgical or diagnostic procedures.
Dosage & Administration
Oral dosage:
- For adults: 7.5-15 mg daily.
- In elderly and debilitated patients: The recommended dose is 7.5 mg.
- In premedication: 15 mg of Midazolam should be given 30-60 minutes before the procedure.
Intravenous administration:
- Endoscopic or Cardiovascular Procedures: In healthy adults, the initial dose is approximately 2.5 mg. In cases of severe illness and in elderly patients, the initial dose must be reduced to 1 to 1.5 mg.
- Induction of Anesthesia: The dose is 10-15 mg.
Intramuscular administration:
- Adult: 0.07-0.1 mg/kg body weight. The usual dose is about 5 mg.
- Children: 0.15-0.20 mg/kg
- Elderly and debilitated patients: 0.025-0.05 mg/kg
Rectal administration in children:
- For preoperative sedation: Rectal administration of the ampoule solution (0.35-0.45 mg/kg) 20-30 min. before induction of general anesthesia.
Side Effects
At the start of therapy, drowsiness during daytime, confusion, fatigue, headache and muscle weakness may occur which usually disappear with repeated administration. Following parenteral (IV or IM) administration of Midazolam, fluctuations in vital signs have been noted including respiratory depression, apnea, variations in blood pressure and pulse rate.
Pregnancy & Lactation
Midazolam should be avoided during pregnancy unless there is no safer alternative. Since Midazolam passes into breast milk, it should not be administered to breast-feeding mothers.
Precautions & Warnings
Midazolam IV should be administered very slowly.
Overdose Effects
Extreme overdosage may lead to coma, areflexia, cardiorespiratory depression and apnea. The effects of overdosage can be controlled with benzodiazepine antagonist flumazenil.
Storage Conditions
Protect from light and moisture, store in cool and dry place. Keep out of the reach of children.
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