Contine -Tablet (Controlled Release) 200 mg/pcs

৳  1.60

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Generic Name: Theophylline
Therapeutic class: Oral Antiasthmatics (Respiratory Tract Preparations)
Manufacturer:Aristopharma Ltd

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Indications

Theophylline is indicated for the-

  • Control of acute asthma.
  • Management of chronic asthma (For both Symptomatic and prophylactic treatment).
  • For controlling nocturnal asthma and early morning wheezing.
  • Management of chronic obstructive lung disease (Chronic bronchitis and emphysema) and acute exacerbation of chronic obstructive lung disease.
  • Control of apnea of pre-maturity.

Dosage & Administration

The dose of theophylline must be individualized on the basis of peak serum theophylline concentration measurements in order to achieve a dose that will provide maximum potential benefit with minimal risk of adverse effects. Most of the sustained release preparations may be administered every 12 hours in adults while administration every 8 hours may be necessary in some children with markedly rapid hepatic
metabolism of theophylline. The recommended maintenance dose within accepted therapeutic range is as follows :

  • 16 years or older: 10 mg/Kg/day (Do not exceed 900 mg/day)
  • 12 years-15 years: 13 mg/Kg/day
  • 9-11 years: 16 mg/Kg/day
  • 1 year-8 years: 24-24 mg/Kg/day
  • 6 months-1 year: 12-18 mg/Kg/day
  • 1-6 months: 10 mg/Kg/day.

Side Effects

Generally side effects are rare at normal dosage. It may include gastrointestinal discomfort, headache, nausea, insomnia and hypotension. CNS stimulation and diuresis may also occur, especially in children.

Pregnancy & Lactation

It is not known whether Theophylline can cause foetal harm when administered to pregnant woman. Xanthines should be given to a pregnant woman only if clearly needed. Theophylline is excreted into breast milk and may cause irritability or other signs of mild toxicity in nursing human infants. Serious adverse effects in the infant are unlikely unless the mother has toxic serum Theophylline concentrations.

Precautions & Warnings

Careful consideration is needed for various interacting drugs and physiologic conditions that can alter Theophylline clearance. Dosage adjustment is required prior to initiation of Theophylline therapy, prior to increases in Theophylline dose, and during follow up. The dose of Theophylline selected for initiation of therapy should be low and, if tolerated, increased slowly over a period of time.

Use in Special Populations

Pediatrics use: The clearance of Theophylline is very low in neonates. Careful attention to dosage selection and monitoring of serum Theophylline concentrations are required in pediatric patients.

Therapeutic Class

Bronchodilator, Theophylline & related drugs

Storage Conditions

Keep all medicines out of reach of children. Store in a cool and dry place, protected from light.

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Contine - Tablet (Controlled Release)200 mg aristopharma

Contine -Tablet (Controlled Release) 200 mg/pcs

৳  1.60

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