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Defrol – 40000 IU Capsule/pcs
৳ 35.00
Generic Name: Cholecalciferol EP (Vitamin D3)
Therapeutic class: Plain Vitamin (Plain Vitamins & Minerals)
Manufacturer: ACME Laboratories Ltd
Note: চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications
Colecalciferol (Vitamin D3) is indicated in the treatment & prevention of Vitamin D3 deficiency. It is also indicated as an adjunct to specific therapy for osteoporosis in patients with vitamin D3 deficiency.
Dosage & Administration
For capsule: Adults:
- Treatment of Vitamin D3 deficiency: 40000 IU once weekly for 7 weeks. Doses for maintenance therapy is 1400-2000 IU/day. To confirm the target level of 25 hydroxyvitamin D, measurement of it should be determined 3-4 months after initiating the maintenance therapy.
- Prevention of Vitamin D3 deficiency: 20000 IU every 4 weeks. Higher doses may be required in certain situations.
- Addition to specific therapy for osteoporosis: 20000 IU once a month.
For capsule: Children (12-18 years):
- Treatment of Vitamin D3 deficiency: 20000 IU once every 2 weeks for 6 weeks.
- Prevention of Vitamin D3 deficiency: 20000 IU every 6 weeks.
For film-coated tablet: 1000 IU (1-2 tablets) daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal.
For oroflash or chewable tablets: 1000 IU to 2000 IU daily, or as directed by physician. Take the medicine with food or within 1 hour after a meal. Place the tablet in mouth swallow after chewing.
For Syrup:
For patients with risk of Cholecalciferol deficiency:
- 0-1 yr: 400 IU/ day (2 ml)
- >1 Yr: 600 lU/ day (3 ml)
For Cholecalciferol deficient patients:
- 0-1 yr: 2000 IU/ day (+50000 IU/week ) for 6 weeks
- 1 -18 yrs: 2000 IU/ day for 6 weeks.
Injection: Prevention:
- Infants receiving Vitamin D enriched milk: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 6 months.
- Nursed infants or infants not receiving Vitamin D enriched milk or young children up to 5 years of age: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months.
- Adolescents: 1 ampoule (1ml) i.e. 2,00000 I.U. every 6 months during winter.
- Pregnancy: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. from the 6th or 7th month of pregnancy.
- Elderly: 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. every 3 months. Digestive disorders, concomitant treatment with antiepileptics & other particular condition not described above; 1/2 ampoule (0.5ml) i.e. 1,00000 I.U. or 1 ampoule (1ml) i.e. 2,00000 I.U. every 3 or 6 months.
Injection: Vitamin D deficiency:
- 1 ampoule (1ml) i.e. 2,00000 I.U. which can be repeated 1 to 6 months later. Or, as directed by the registered physician.
Side Effects
The general side effects are hypercalcaemia, hypercalciuria, skin rash, pruritus, urticaria, nausea, abdominal pain.
Pregnancy & Lactation
Studies have shown safe use of doses up to 4000 IU during pregnancy. The recommended daily intake for pregnant women is 400 IU, however, in women who are considered to be Vitamin D3 deficient a higher dose may be required. During pregnancy women should follow the advice of their medical practitioner as their requirements may vary depending on the severity of their disease and their response to treatment
Vitamin D3 and its metabolites are excreted in breast milk. Overdose in infants induced by nursing mothers has not been observed; however, when prescribing additional vitamin D3 to a breast-fed child the practitioner should consider the dose of any additional vitamin D3 given to the mother.
Precautions & Warnings
It should be used with caution in patients with impaired renal function.
Use in Special Populations
The safety & efficacy of Vitamin D3 in children under 12 years have not been established.
Overdose Effects
It can lead to hypervitaminosis D.
Storage Conditions
Keep below 30º C temperature, protected from light & moisture. Keep out of the reach of children.
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