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Etodolac is indicated-
- For acute and long-term use in the management of signs and symptoms: Osteoarthritis, Rheumatoid arthritis
- For the management of acute pain
- Acute gout
Dosage & Administration
Adults and over 18 years:
- Etodolac 300 mg capsule: 600 mg daily in 1-2 divided doses
- Etodolac 600 mg ER tablet: Once daily
Pediatric: Safety and effectiveness in pediatric patients below the age of 18 years have not been established.
The common side effects of Etodolac involve the gastrointestinal system. It can cause abdominal pain, constipation, diarrhea, dyspepsia, flatulence, heartburn, nausea, Gl ulcers, vomiting. Other events including abnormal renal function, anemia, dizziness, edema, elevated liver enzymes, headaches, increased bleeding time, pruritis, rashes, tinnitus etc.
Pregnancy & Lactation
There are no adequate and well-controlled studies in pregnant women. It should be used in pregnancy only if the potential benefit justifies the potential risk to the fetus. It is not known whether Etodolac is excreted in human milk. A decision should be made whether to discontinue nursing or to discontinue the drug taking into account the importance of the drug to the mother.
Precautions & Warnings
Etodolac should be given with caution in patients with severe hepatic reactions, pre existing asthma, fluid retention, hypertension or heart failure. If clinical sings and symptoms consistent with liver disease develop, or if systemic manifestations occur (e.g. eosinophilia, rash etc.), it should be discontinued.
Symptoms following acute NSAID overdose are usually limited to lethargy, drowsiness, nausea, vomiting, and epigastric pain which are generally reversible with supportive care.
Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Do not store above 30°C. Keep away from light and out of the reach of children.