No products in the cart.
Roll over image to zoom in
Emiston – IM/IV Injection 4 ml ampoule /pcs
৳ 25.08
Generic Name: Ondansetron HCl
Therapeutic class: Antiemetic and Antinauseant (CNS Preparations)
Manufacturer:Ibn-Sina Pharmaceuticals Ltd
Note: চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications
Ondansetron is a serotonin subtype 3 (5-HT3) receptor antagonist indicated:
- Prevention of nausea and vomiting associated with initial and repeat courses of emetogenic cancer chemotherapy.
- Prevention and treatment of post-operative nausea and vomiting.
- Prevention of radiotherapy-induced nausea and vomiting.
Dosage & Administration
Chemotherapy-Induced Nausea and Vomiting-
Adults, Pediatric patients (6 months to 18 years):
- 8 mg tablet/orodispersible tablet: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose.
- 4 mg orodispersible tablet: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose.
- Injection: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes.
Radiotherapy-Induced Nausea and Vomiting-
Adults:
- 8 mg tablet/orodispersible tablet: Initial Dose: 8 mg orally 1 to 2 hours before radiotherapy. Post Radiotherapy: 8 mg orally every 8 hours for up to 5 days after a course of treatment.
- 4 mg orodispersible tablet: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose.
- Injection: Three 0.15 mg/kg doses, up to a maximum of 16 mg per dose, infused intravenously over 15 minutes.
Postoperative Nausea and Vomiting-
Adults:
- 8 mg tablet/orodispersible tablet: 16 mg given as two 8 mg tablets
- 4 mg orodispersible tablet: 16 mg
- Injection: 4 mg
Pediatrics (>40 kg): Injection: 4 mg
Pediatrics (40 kg): Injection: 0.1 mg/kg
Side Effects
The most common adverse reactions in chemotherapy-induced nausea and vomiting (incidence 7%) are diarrhea, headache and fever. The most common adverse reactions in postoperative nausea and vomiting in adults is headache (incidence 10%), and in pediatric patients aged 1 to 24 months is diarrhea (incidence 2%).
Pregnancy & Lactation
Pregnancy Category B. Ondansetron is excreted in the breast milk of rats. It is not known whether ondansetron is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when ondansetron is administered to a nursing woman.
Precautions & Warnings
Hypersensitivity reactions, including anaphylaxis and bronchospasm, have been reported with or without known hypersensitivity to other selective 5-HT3 receptor antagonists. QT prolongation occurs in a dose-dependent manner.
Use in Special Populations
Geriatric Use: Dosage adjustment is not needed in patients over the age of 65.
Hepatic Impairment: A total daily dose of 8mg should not be exceeded (patients with severe hepatic impairment).
Renal Impairment: No dosage adjustment is recommended.
Hepatic Impairment: A total daily dose of 8mg should not be exceeded (patients with severe hepatic impairment).
Renal Impairment: No dosage adjustment is recommended.
Storage Conditions
Store at temperature not exceeding 30ºC in a dry place. Protect from light and moisture.
Reviews
There are no reviews yet.