Name: Fixocard - Tablet (5mg + 50mg)/pcs
Brand: Incepta Pharmaceuticals Ltd
SKU: Fixocard - Tablet (5mg + 50mg)
Price: 6.00 BDT
Availability: InStock

Indications

This is indicated in-

Patients with essential hypertension
Patients with angina pectoris & hypertension as co-existing diseases
ln post Ml patients
ln patients with refractory angina pectoris where nitrate therapy has failed.

Dosage & Administration

Adult: This therapy is initiated with a single dose of this preparation depending upon the therapeutic response, titration of the dosage is recommended.

In elderly patients: It is advisable to initiate the therapy with ½ tablet of fixed dose combination of Amlodipine & Atenolol, i.e., 2.5 mg of Amlodipine & 25 mg Atenolol.

Side Effects

The combination of Amlodipine and Atenolol is well tolerated. Overall side-effects include
fatigue, headache, edema, nausea, drowsiness, anxiety and depression.

Pregnancy & Lactation

The combination should be used during pregnancy only if the expected benefit outweighs the potential fetal risk. The combination should not be used by nursing mothers. If its use is considered necessary, breast-feeding should be stopped.

Precautions & Warnings

Bronchospasm: The combination should be used with caution in patients with airway obstruction.

Renal impairment: The combination can be used in patients with renal impairment. However, caution may be necessary if the creatinine clearance is less than 30 ml/min because of possible reduction in the excretion of unchanged Atenolol.

Hepatic impairment: Caution may be necessary in the use of the combination in patients with severe liver damage because of prolongation of the elimination half-life of Amlodipine.

Drug withdrawal: Since coronary heart disease may exist without being recognized, patients should be warned against stopping the drug suddenly. Any discontinuation should be gradual and under observation.

Overdose Effects

Though not documented, hypotension and less frequently congestive cardiac failure may occur in cases of overdosage. Unabsorbed drugs may be removed by gastric lavage or administration of activated charcoal. Symptomatic treatment is suggested.