Infovir- 10 mg Tablet/pcs
- Brand: Incepta Pharmaceuticals Ltd
Generic Name: Adefovir Dipivoxil
Therapeutic class: Antivirals (Systemic Antifungal, Antiviral and Antiprotozoal Agents)
Manufacturer: Incepta Pharmaceuticals Ltd.
The recommended dose of Adefovir in chronic hepatitis B patients with adequate renal function is 10 mg, once daily, taken orally, without regard to food.
Pregnancy & Lactation
Precautions & Warnings
Use in Special Populations
Pediatric use: Safety and effectiveness in pediatric patients have not been established.
Geriatric use: In general, caution should be exercised when prescribing to elderly patients since they have greater frequency of decreased renal or cardiac function due to concomitant disease or other drug therapy.
Dose Adjustment in Renal Impairment: the dosing interval of Adefovir should be adjusted in patients with baseline creatinine clearance <50 ml/min using the following suggested guidelines:
- CrCl ≤ 50 ml/min: 10 mg
- CrCl 20-49 ml/min: 10 mg every 48 hours
- CrCl 10-19 ml/min: 10 mg every 72 hours
- Haemodialysis patients: 10 mg every 7 days following dialysis
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