Ivaprex  – Tablet 5 mg/pcs

৳  20.00

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Generic Name: Ivabradine
Therapeutic class: Antianginal Drugs (Cardiovascular Preparations)                                   Manufacturer : Incepta Pharmaceuticals Ltd.

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Indications

Symptomatic treatment of chronic stable angina pectoris in coronary artery disease patients with normal sinus rhythm. Ivabradine is indicated:

  • In patients unable to tolerate or with a contra-indication to the use of beta-blockers or
  • In combination with beta-blockers in patients inadequately controlled with an optimal beta-blocker dose and whose heart rate is > 60 bpm.

Dosage & Administration

Adult: The usual recommended starting dose of Ivabradine is 5 mg twice daily which may be increased after 3-4 weeks of treatment to 7.5 mg twice daily, depending on therapeutic response. Usual dose is 1 tablet in the morning and 1 tablet in the evening during meals. If the heart rate decreases persistently below 50 bpm at rest or if symptoms related to bradycardia, the dose must be adjusted downwards to 2.5 mg twice daily (one half of the 5 mg tablet twice daily). Treatment must be discontinued if heart rate remains below 50 bpm or symptoms of bradycardia persist.

Elderly: Consider a lower starting dose (2.5 mg twice daily i.e. one half 5 mg tablet twice daily)

Side Effects

Visual symptoms, blurred vision, bradycardia, 1st degree AV block, ventricular extrasystoles, headaches, and dizziness.

Pregnancy & Lactation

Studies in rats have shown no effect on fertility in males and females. There are no or limited amount of data from the use of ivabradine in pregnant women. Therefore, ivabradine is contra indicated during pregnancy. Animal studies indicate that ivabradine is excreted in milk. Therefore, ivabradine is contra-indicated during breast-feeding.

Precautions & Warnings

Mild to moderate hypotension, atrial fibrillation, patients with congenital QT syndrome or treated with QT wave prolonging medicinal products, Moderate hepatic insufficiency, severe renal insufficiency.

Use in Special Populations

  • Renal insufficiency: Use with caution in patients with creatinine clearance
  • Hepatic impairment: Use with caution in patients with moderate hepatic impairment; Contraindicated in severe hepatic impairment.
  • Children and adolescents: Not recommended.

Therapeutic Class

Other Anti-anginal & Anti-ischaemic drugs

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

 

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Ivaprex Tablet 5 mg Incepta Pharmaceuticals Ltd.

Ivaprex  - Tablet 5 mg/pcs

৳  20.00

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