Migrium – 5 mg Tablet/pcs

৳  3.50

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Generic Name: Flunarizine HCl
Therapeutic class: Anti-migraine (CNS Preparations)
Manufacturer: Opso Saline Ltd

Note: চিকিৎসকের পরামর্শ মোতাবেক  ঔষধ সেবন করুন




Flunarizine is indicated for

  • Prophylaxis of classic (with aura) or common (without aura) migraine
  • Symptomatic treatment of vestibular vertigo (due to a diagnosed functional disorder of the vestibular system).
  • Peripheral Vascular Disease (PVD)
  • Motion sickness
  • Refractory epilepsy resistant to conventional antiepileptic therapy.

Dosage & Administration

Migraine Prophylaxis:

  • Starting Dose: 10 mg at night in patients less than 65 years of age and 5 mg daily in patients older than 65 years. If, during this treatment depressive, extrapyramidal or other unacceptable symptoms occur, administration should be discontinued. If, after 2 months of this initial treatment, no significant improvement is observed, the patient should be considered a non-responder and administration should be discontinued.
  • Maintenance Treatment: If a patient is responding satisfactorily and if a maintenance treatment is needed, the dose should be decreased to 5 days treatment at the same daily dose with two successive medicine free days every week. Even if the prophylactic maintenance treatment is successful and well tolerated, it should be interrupted after 6 months and it should be re-initiated only if the patient relapses.

Peripheral Vascular disease: 10 mg twice daily, up to 30 mg per day if required.

Vertigo & motion sickness: 10-20 mg daily for adults and 5 mg daily for children (> 40 kg).

Epileptic seizure: 15-20 mg daily in adults and 5 to 10 mg daily for children as an add-on therapy

Side Effects

Drowsiness and/or fatigue, as well as weight gain and/or increased appetite may occur. The following adverse experiences have been reported during chronic treatment with Flunarizine: depression, of which female patients with a history of depressive illness may be particularly at risk; extrapyramidal symptoms (such as bradykinesia, rigidity, akathisia, orofacial dyskinesia, tremor), of which elderly patients seem particularly at risk. Infrequently reported adverse reaction are: heartburn; nausea; gastralgia; insomnia; anxiety; galactorrhoea; dry mouth; muscle ache; skin rash.

Pregnancy & Lactation

Safety in pregnancy and lactation has not been established.

Precautions & Warnings

Flunarizine may lead to drowsiness which is aggravated by the simultaneous intake of alcohol or other central nervous system depressants. Patients should be cautioned against driving motor vehicles or performing other potentially hazardous tasks where a loss of mental alertness may lead to accidents. Flunarizine is not suited for aborting a migraine attack. The possible occurrence of an attack is therefore no reason to increase the dose of Flunarizine. This treatment may give rise to extrapyramidal and depressive symptoms and reveal Parkinsonism, especially in predisposed patients such as the elderly. Flunarizine should therefore be used with caution in such patients.

Therapeutic Class

Miscellaneous prophylactic migraine preparations

Storage Conditions

Keep below 30°C temperature, away from light & moisture. Keep out of the reach of children.

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন

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Migrium - 5 mg Tablet/pcs

৳  3.50

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