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Palosis – 0.5 mg Capsule/pcs
৳ 20.00
Generic Name: Palonosetron
Therapeutic class: Antiemetic and Antinauseant (CNS Preparations)
Manufacturer: Eskayef Bangladesh Ltd
Note: চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন
Indications
Palonosetron indicated in-
- Acute and delayed nausea and vomiting
- Uncontrolled nausea and vomiting
- Chemotherapy-induced nausea and vomiting (CINV): Acute CINV resulting in on the day of treatment with certain types of chemotherapy
- Delayed CINV resulting in on days later with certain types of chemotherapy
- Radiotherapy-induced nausea and vomiting (RINV)
- Post-operative & Post-discharge nausea and vomiting (PONV & PDNV).
Dosage & Administration
Usual dosage: Adult tablet dosage: 0.5 mg daily. Adult IV dosage: A single IV dose of 0.075 mg should be administered over 10 seconds.
Chemotherapy-induced nausea and vomiting: Adult tablet dosage: 0.5 mg administered approximately 1 hour prior to the start of chemotherapy. Adult IV dosage: A single IV dose of 0.25 mg should be administered over 30 seconds approximately 30 minutes before the start of chemotherapy.
Radiotherapy-induced nausea and vomiting: A single IV dose of 0.25 mg should be administered over 30 seconds approximately 30 minutes before each week of radiation fraction.
Post-operative nausea and vomiting: A single IV dose of 0.075 mg should be administered over 10 seconds immediately before induction of anesthesia.
Children dosage: (1 month to 17 years): A single IV dose at 20 mcg/kg body weight. Which maximum dose is 1.5 mg.
Side Effects
The most common adverse reactions are headaches and constipation.
Pregnancy & Lactation
Pregnancy category ‘B’. It is not known whether Palonosetron is excreted in breast milk.
Use in Special Populations
Use in elderly patients: No dosage adjustment is recommended in elderly patients >65 years of age.
Use in Children: (1 month to 10 years): A single IV dose at 20 mcg/kg body weight. Which maximum dose is 1.5 mg.
Use in patients with impaired renal and hepatic function: No dosage adjustment is recommended in patients with renal and hepatic dysfunction.
Overdose Effects
There is no known antidote to Palonosetron. Overdose should be managed with supportive care.
Storage Conditions
Store in a cool & dry place, protected from light.
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