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sorafenib

What is Sorafenib?

Sorafenib is used for Liver cancer, Kidney cancer, Thyroid cancer and other conditions. This salt may also be used for purposes not listed in this medication guide.

Sorafenib Uses

Sorafenib is used for the treatment, control, prevention, & improvement of the following diseases, conditions and symptoms:

    • Liver cancer
    • Kidney cancer
    • Thyroid cancer

Sorafenib Working, Mechanism of Action and Pharmacology

Sorafenib improves the patient's condition by performing the following functions:

    • Slowing down the rate of growth of cancer cells.

Sorafenib - Side-effects

The following is a list of possible side-effects that may occur in medicines that contain Sorafenib. This is not a comprehensive list. These side-effects are possible, but do not always occur. Some of the side-effects may be rare but serious. Consult your doctor if you observe any of the following side-effects, especially if they do not go away.

    • Nausea
    • Loss of appetite
    • Constipation
    • Indigestion
    • Difficulty in swallowing
    • Distortion of the sense of taste

Sorafenib - Precautions & How to Use

Before using this drug, inform your doctor about your current list of medications, over the counter products (e.g. vitamins, herbal supplements, etc.), allergies, pre-existing diseases, and current health conditions (e.g. pregnancy, upcoming surgery, etc.). Some health conditions may make you more susceptible to the side-effects of the drug. Take as directed by your doctor or follow the direction printed on the product insert. Dosage is based on your condition. Tell your doctor if your condition persists or worsens. Important counseling points are listed below.

    • Consult a doctor if you are suffering from high blood pressure, bleeding problems, chest pain, heart problems, kidney problems or liver disease
    • Monitoring of blood calcium levels and thyroid hormones, fluid balance and electrolytes is needed
    • Planning to become pregnant or are breastfeeding
    • Take caution if you are going to have a surgery or have been recently operated upon

Sorafenib - Drug Interactions

If you use other drugs or over the counter products at the same time, the effects of Sorafenib may change. This may increase your risk for side-effects or cause your drug not to work properly. Tell your doctor about all the drugs, vitamins, and herbal supplements you are using, so that you doctor can help you prevent or manage drug interactions. Sorafenib may interact with the following drugs and products:

    • Carbamazepine
    • Dexamethasone
    • Ketoconazole
    • Neomycin
    • Phenobarbital
    • Phenytoin

Sorafenib - Contraindications

Hypersensitivity to Sorafenib is a contraindication. In addition, Sorafenib should not be used if you have the following conditions:

    • Hypersensitivity

Other important Information on Sorafenib

Missing a dose

In case you miss a dose, use it as soon as you notice. If it is close to the time of your next dose, skip the missed dose and resume your dosing schedule. Do not use extra dose to make up for a missed dose. If you are regularly missing doses, consider setting an alarm or asking a family member to remind you. Please consult your doctor to discuss changes in your dosing schedule or a new schedule to make up for missed doses, if you have missed too many doses recently.

Overdosage of Sorafenib

Do not use more than prescribed dose. Taking more medication will not improve your symptoms; rather they may cause poisoning or serious side-effects. If you suspect that you or anyone else who may have overdosed of Sorafenib, please go to the emergency department of the closest hospital or nursing home. Bring a medicine box, container, or label with you to help doctors with necessary information.

Do not give your medicines to other people even if you know that they have the same condition or it seems that they may have similar conditions. This may lead to overdosage.

Please consult your physician or pharmacist or product package for more information.

Storage of Sorafenib

Store medicines at room temperature, away from heat and direct light. Do not freeze medicines unless required by package insert. Keep medicines away from children and pets.

Do not flush medications down the toilet or pour them into drainage unless instructed to do so. Medication discarded in this manner may contaminate the environment. Please consult your pharmacist or doctor for more details on how to safely discard Sorafenib.

Expired Sorafenib

Taking a single dose of expired Sorafenib is unlikely to produce an adverse event. However, please discuss with your primary health provider or pharmacist for proper advice or if you feel unwell or sick. Expired drug may become ineffective in treating your prescribed conditions. To be on the safe side, it is important not to use expired drug. If you have a chronic illness that requires taking medicine constantly such as heart condition, seizures, and life-threatening allergies, you are much safer keeping in touch with your primary health care provider so that you can have a fresh supply of unexpired medications.

Sorafenib - Frequently asked Questions

How long do I need to use Sorafenib before I see improvement of my conditions?

Users have reported 2 weeks and 1 month as the most common time it takes before they saw improvements in their conditions. These times may not be reflective of what you may experience or how you should use this medicine. Please consult with your doctor to check how long do you need to use Sorafenib.

Should I consume Sorafenib empty stomach, before food or after food?

Users have most commonly reported consuming Sorafenib before food. However, this may not be reflective of how you should consume this medicine. Please follow your doctor's advice on how you should use this medicine.

Is it safe to drive or operate heavy machinery when consuming?

If you experience drowsiness, dizziness, hypotension or a headache as side-effects when using Sorafenib medicine then it may not be safe to drive a vehicle or operate heavy machinery. One should not drive a vehicle if using the medicine makes you drowsy, dizzy or lowers your blood-pressure extensively. Pharmacists also advise patients not to drink alcohol with medicines as alcohol intensifies drowsiness side-effects. Please check for these effects on your body when using Sorafenib. Always consult with your doctor for recommendations specific to your body and health conditions.

Is this medicine or product addictive or habit forming?

Most medicines don't come with a potential for addiction or abuse. Usually, government's categorizes medicines that can be addictive as controlled substances. Examples include schedule H or X in India and schedule II-V in the US. Please consult the product package to make sure that the medicine does not belong to such special categorizations of medicines. Lastly, do not self-medicate and increase your body's dependence to medicines without the advice of a doctor.

Can it be stopped immediately or do I have to slowly ween off consumption?

Some medicines need to be tapered or cannot be stopped immediately because of rebound effects. Please consult with your doctor for recommendations specific to your body, health and other medications that you may be using.

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